{"id":6289,"date":"2017-10-05T21:42:57","date_gmt":"2017-10-05T21:42:57","guid":{"rendered":"http:\/\/cchc-herald.org\/eu\/?page_id=6289"},"modified":"2020-10-02T21:52:41","modified_gmt":"2020-10-02T21:52:41","slug":"%e6%96%b0%e8%81%9e%e7%9f%ad%e8%ab%96-%e6%bd%98%e5%a4%9a%e6%8b%89%e7%9a%84%e7%9b%92%e5%ad%90","status":"publish","type":"page","link":"http:\/\/eu.cchc-herald.org\/?page_id=6289","title":{"rendered":"\u65b0\u805e\u77ed\u8ad6: \u6f58\u591a\u62c9\u7684\u76d2\u5b50"},"content":{"rendered":"<p>2017\u5e7410\u6708<br \/>\n\u5b97\u6dd1<\/p>\n<p>8\u670815\u65e5\uff0c2017\u5e74\u963f\u723e\u4f2f\u5c3c\u751f\u7269\u91ab\u5b78\u734e(Albany Medical Center Prize in Medicine and Biomedical Research)\uff0c\u6388\u4e88\u4e94\u540d\u300c\u5728\u57fa\u56e0\u7de8\u8f2f\u9818\u57df\u505a\u51fa\u5148\u9a45\u6027\u8ca2\u737b\u300d\u7684\u79d1\u5b78\u5bb6\u3002<\/p>\n<h2>\u25ce\u57fa\u56e0\u7de8\u8f2f<\/h2>\n<p>\u7f8e\u570b\u4fc4\u52d2\u5ca1\u885b\u751f\u79d1\u6280\u5927\u5b78(Oregon Health and Science University)\u79d1\u5b78\u5bb6\uff0c\u5229\u7528CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u5c0d\u672a\u88ab\u690d\u5165\u5b50\u5bae\u524d\u7684\u4eba\u985e\u80da\u80ce\uff0c\u9032\u884c\u8207\u907a\u50b3\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5(HCM)\u6709\u95dc\u7684\u57fa\u56e0\u8b8a\u7570\u4e4b\u4fee\u6b63\u3002<br \/>\n\u7814\u7a76\u5718\u968a\u5c07\u4f86\u81ea\u5065\u5eb7\u6350\u8d08\u8005\u7684\u5375\u6bcd\u7d30\u80de\uff0c\u8207\u651c\u5e36MYBPC3\u57fa\u56e0\u8b8a\u7570\u7684\u7cbe\u5b50\u7d50\u5408\uff0c\u57f9\u80b2\u51fa\u53d7\u7cbe\u5375\uff1b\u7136\u5f8c\u5229\u7528CRISPR-Cas9\uff0c\u5728\u8b8a\u7570\u57fa\u56e0\u5e8f\u5217\u4e0a\u526a\u51fa\u7f3a\u53e3\uff0c\u89c0\u5bdf\u4eba\u985e\u80da\u80ce\u5982\u4f55\u4fee\u5fa9\u9019\u4e9bDNA\u7f3a\u53e3\u3002\u901a\u904e\u53c3\u7167\u6b63\u5e38\u6350\u8d08\u8005\u7684\u672a\u8b8a\u7570\u7248\u672c\uff0c\u767c\u73fe\u5728\u591a\u6578\u60c5\u6cc1\u4e0b\uff0c\u640d\u50b7\u5f88\u5feb\u88ab\u4fee\u5fa9\u3002<\/p>\n<p>HCM\u7684\u60a3\u75c5\u7387\u70ba\u4e94\u767e\u5206\u4e4b\u4e00\uff0c\u5373\u6bcf500\u4eba\u4e2d\u5373\u6709\u4e00\u4eba\u7f79\u60a3\uff1b\u53ea\u8981\u907a\u50b3\u4e00\u4efdMYBPC3\u57fa\u56e0\u4e2d\u7684\u8b8a\u7570\u7248\u672c\u5c31\u80fd\u81f4\u75c5\uff0c\u5c0e\u81f4\u5fc3\u539f\u6027\u731d\u6b7b\u548c\u5fc3\u529b\u8870\u7aed\uff1b\u7576\u524d\u7684\u6cbb\u7642\u65b9\u6848\u53ea\u53ef\u7de9\u89e3\u75c7\u72c0\uff0c\u4e0d\u80fd\u89e3\u6c7a\u907a\u50b3\u554f\u984c\u3002<\/p>\n<p>\u5f9e\u5be6\u9a57\u516c\u4f48\u7684\u7d50\u679c\u770b\uff0cCRISPR-Cas9\u5b9a\u5411\u7cbe\u78ba\uff0c\u672a\u51fa\u73fe\u812b\u9776\u8b8a\u7570\uff0c\u4e5f\u672a\u751f\u6210\u65b0\u7684\u7a81\u8b8a\u3002\u9019\u61c9\u8a72\u662f\u597d\u6d88\u606f\uff0c\u5f9e\u539f\u7406\u4e0a\u8b49\u660eCRISPR\u7de8\u8f2f\u80da\u80ce\u5b8c\u5168\u53ef\u884c\uff0c\u4e0d\u50c5\u53ef\u4ee5\u9020\u798fHCM\u60a3\u8005\uff0c\u800c\u4e14\u5047\u4ee5\u6642\u65e5\u5fc5\u53ef\u64f4\u53ca\u5176\u4ed6\u907a\u50b3\u75c5\u8005\u2026\u2026\u4f46\u8a55\u8ad6\u5bb6\u537b\u8a8d\u70ba\uff0c\u9019\u4e00\u5be6\u9a57\u7684\u5c55\u958b\u610f\u5473\u8457\u6f58\u591a\u62c9\u9b54\u76d2\u88ab\u6253\u958b\uff1b\u7f8e\u570b\u60c5\u5831\u754c\u751a\u81f3\u5c07CRISPR\u7a31\u70ba\u6f5b\u5728\u7684\u300c\u5927\u898f\u6a21\u6bc0\u6ec5\u6027\u6b66\u5668\u300d\uff01\u539f\u56e0\u4e26\u975e\u53ea\u662fDNA\u7de8\u8f2f\u4e26\u690d\u5165\u6bcd\u9ad4\u5728\u7f8e\u570b\u975e\u6cd5\uff0c\u800c\u5728\u65bc\u5c0d\u50f9\u503c\u9818\u57df\u7684\u64d4\u5fc3\u2014\u2014\u6b77\u53f2\u4e00\u518d\u986f\u793a\uff0c\u79d1\u5b78\u6bcf\u53d6\u5f97\u91cd\u5927\u9032\u6b65\uff0c\u4eba\u985e\u7684\u63a0\u596a\u4fbf\u96a8\u4e4b\u9032\u5165\u66f4\u9ad8\u968e\u6bb5\u3002<\/p>\n<h2>\u25ce\u5b9a\u5236\u5b30\u5152<\/h2>\n<p>\u6279\u8a55\u8005\u8a8d\u70ba\uff0c\u57fa\u56e0\u7de8\u8f2f\u6703\u6253\u958b\u5b9a\u5236\u5b30\u5152\u7684\u5927\u9580\uff0c\u5141\u8a31\u9078\u64c7\u5b55\u80b2\u5177\u6709\u67d0\u7a2e\u7279\u5fb5\u7684\u5b30\u5152\u3002\u9019\u986f\u7136\u4e0d\u662f\u675e\u4eba\u6182\u5929\u3002<\/p>\n<p>\u7d10\u7d04\u65b0\u5e0c\u671b\u4e0d\u5b55\u75c7\u8a66\u7ba1\u5b30\u5152\u4e2d\u5fc3(New Hope Fertility Center)\u7684\u5f35\u9032\u91ab\u751f\uff0c\u65e2\u4ee5\u9996\u5275\u300c\u4e09\u7236\u6bcd\u300dDNA\u65b0\u751f\u5152\u800c\u805e\u540d\u3002\u7f8e\u570b\u806f\u90a6\u98df\u85e5\u7ba1\u7406\u5c40(FDA)\u7981\u6b62\u5176\u5ba3\u50b3\u3001\u4f7f\u7528\u6216\u8a66\u9a57\u300c\u4e09\u4eba\u300dDNA\u5b55\u80b2\u65b0\u751f\u5152\uff0c\u5f35\u9032\u8207\u7f8e\u570b\u91ab\u7642\u5718\u968a\uff0c\u4fbf\u65bc2016\u5e744\u6708\uff0c\u5728\u58a8\u897f\u54e5\u5b55\u80b2\u51fa\u5168\u4e16\u754c\u7b2c\u4e00\u500b\u64c1\u6709\u300c\u4e09\u4eba\u300dDNA\u7684\u65b0\u751f\u5152\u54c8\u6851(Abrahim Hassan)\u3002<\/p>\n<p>\u5229\u7528\u65b0\u6280\u8853\u62ef\u6551\u751f\u547d\u7576\u7136\u662f\u597d\u4e8b\uff0c\u554f\u984c\u662f\u4eba\u6027\u4e26\u4e0d\u80fd\u4fdd\u8b49\u53ea\u505a\u597d\u4e8b\u3002\u8c48\u4e0d\u898b\uff0c\u4eba\u8166\u8d8a\u4f86\u8d8a\u8070\u660e\u3001\u667a\u5546\u8d8a\u4f86\u8d8a\u9ad8\uff0c\u4eba\u5fc3\u537b\u8d8a\u4f86\u8d8a\u6557\u58de\u3001\u60c5\u5546\u8d8a\u4f86\u8d8a\u4f4e\uff1f\u300c\u4e09\u4eba\u300dDNA\u8a66\u7ba1\u5b30\u5152\u8207\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\u4e0d\u540c\uff0c\u4f46\u90fd\u53ef\u6d3e\u751f\u5404\u7a2e\u5229\u76ca\u751a\u81f3\u7279\u6b0a\uff0c\u800c\u9019\u5f88\u53ef\u80fd\u5c0e\u81f4\u4eba\u985e\u5171\u540c\u9ad4\u88ab\u6495\u88c2\uff0c\u56e0\u70ba\u4eba\u985e\u6839\u672c\u7121\u6cd5\u5efa\u7acb\u8d77\u7d71\u4e00\u7684\u9053\u5fb7\u898f\u7bc4\u6216\u4fe1\u4ef0\u9ad4\u7cfb\uff0c\u5c24\u5176\u662f\u5728\u4eba\u4ee5\u70ba\u81ea\u5df1\u53ef\u4ee5\u4ee3\u66ff\u4e0a\u5e1d\u7684\u6642\u5019\uff0c\u5584\u826f\u7684\u9858\u671b\u4e5f\u6703\u5c0e\u81f4\u4eba\u9593\u5730\u7344\u3002<\/p>\n<h2>\u25ce\u4e0d\u53ef\u9810\u6e2c<\/h2>\n<p>\u57fa\u56e0\u7de8\u8f2f\u6280\u8853\uff0c\u80fd\u5b8c\u5168\u6d88\u9664\u75be\u75c5\u57fa\u56e0\u55ce\uff1f\u5be6\u969b\u4e0a\uff0c\u65e9\u57282015\u5e74\u82072016\u5e74\uff0c\u4e2d\u570b\u7684\u79d1\u5b78\u5bb6\u5c31\u5206\u5225\u5c0d\u4eba\u985e\u53d7\u7cbe\u5375\u4e2d\u5730\u4e2d\u6d77\u8ca7\u8840\u75c7\u76f8\u95dc\u57fa\u56e0\u3001\u827e\u6ecb\u75c5\u6bd2\u76f8\u95dc\u57fa\u56e0\u9032\u884c\u7de8\u8f2f\uff0c\u904e\u7a0b\u4e2d\u96d6\u6709\u6210\u529f\uff0c\u4f46\u540c\u6642\u4e5f\u767c\u751f\u627e\u932f\u76ee\u6a19\u57fa\u56e0\u3001\u7522\u751f\u300c\u812b\u9776\u300d\u6548\u61c9\u3001\u8a08\u5283\u5916\u57fa\u56e0\u8b8a\u7570\u7b49\u554f\u984c\u3002<\/p>\n<p>\u7576\u7136\uff0c\u7f8e\u570b\u79d1\u5b78\u5bb6\u7684\u9019\u6b21\u5be6\u9a57\u4e26\u672a\u767c\u751f\u4e0a\u8ff0\u300c\u610f\u5916\u300d\uff0c\u4f46\u4e26\u4e0d\u610f\u5473\u8457\u5f9e\u6b64\u5c31\u5b89\u5168\u7121\u865e\u3002\u4eba\u985e\u57fa\u56e0\u4fee\u6539\u53ef\u80fd\u907a\u50b3\u5f8c\u4ee3\uff0c\u5982\u679c\u4fee\u6539\u4e86\u65e2\u6210\u932f\u8aa4\uff0c\u537b\u4e5f\u88fd\u9020\u4e86\u65b0\u7684\u932f\u8aa4\uff0c\u5f15\u767c\u5176\u4ed6\u7f3a\u9677\u6216\u75be\u75c5\uff0c\u600e\u9ebc\u8fa6\uff1f\u6709\u4eba\u8a8d\u70ba\uff0c\u53ef\u4ee5\u56b4\u683c\u63a7\u5236\u5728\u5be6\u9a57\u5ba4\u5167\uff0c\u4f46\u662f\u6f58\u591a\u62c9\u7684\u76d2\u5b50\u4e00\u65e6\u6253\u958b\uff0c\u5f8c\u679c\u53ef\u60f3\u800c\u77e5\u3002<\/p>\n<p>\u5927\u91cf\u5730\u3001\u4e0d\u53d7\u63a7\u5236\u5730\u7de8\u8f2fDNA\uff0c\u53c8\u6703\u5982\u4f55\uff1f\u5c0e\u81f4\u4eba\u985e\u6ec5\u7d55\u3002\u4eba\u985e\u7684\u81ea\u6211\u6bc0\u6ec5\uff0c\u5f9e\u4f86\u4e0d\u662f\u6bc0\u65bc\u8166\uff0c\u800c\u662f\u6bc0\u65bc\u5fc3\uff1a\u300c\u4eba\u5fc3\u6bd4\u842c\u7269\u90fd\u8a6d\u8a50\uff0c\u58de\u5230\u6975\u8655\uff0c\u8ab0\u80fd\u8b58\u900f\u5462\uff1f\u300d\uff08\u300a\u8056\u7d93\u2027\u8036\u5229\u7c73\u66f8\u300b\u5341\u4e03\u7ae09\u7bc0\uff09<\/p>\n<div id=\"nav_menu-8\" class=\"widget widget_nav_menu amr_widget\"><h4>2017\u5e748\u6708\u5167\u5bb9<\/h4><div class=\"menu-2017%e5%b9%b410%e6%9c%88%e5%85%a7%e5%ae%b9-container\"><ul id=\"menu-2017%e5%b9%b410%e6%9c%88%e5%85%a7%e5%ae%b9\" class=\"menu\"><li id=\"menu-item-6135\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6135\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6117\">\u5c08\u984c: (\u793e\u8ad6) \u7bc0\u5236\u8207\u81ea\u7531<\/a><\/li>\n<li id=\"menu-item-6136\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6136\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6116\">\u5c08\u984c: \u82ac\u862d\u4eba\u7684\u4f5c\u606f<\/a><\/li>\n<li id=\"menu-item-6137\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6137\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6115\">\u5c08\u984c: \u771f\u7684\u6709\u5fc5\u8981\u8cb7\u55ce\uff1f<\/a><\/li>\n<li id=\"menu-item-6138\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6138\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6114\">\u5c08\u984c: \u5f97\u5230\u771f\u6b63\u7684\u81ea\u7531<\/a><\/li>\n<li id=\"menu-item-6139\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6139\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6113\">\u5c08\u984c: \u7d14\u6f54\u7684\u7537\u5973\u95dc\u4fc2<\/a><\/li>\n<li id=\"menu-item-6140\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6140\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6112\">\u5c08\u984c: \u300c\u5c11\u5403\u4e00\u9ede\u5427\uff01\u300d<\/a><\/li>\n<li id=\"menu-item-6141\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6141\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6111\">\u5c08\u984c: \u5f9e\u601d\u60f3\u4e0b\u624b<\/a><\/li>\n<li id=\"menu-item-6156\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6156\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6151\">\u667a\u6167\u4e4b\u7a97: \u8d95\u5feb\u4fee\u5fa9\u95dc\u4fc2<\/a><\/li>\n<li id=\"menu-item-6157\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6157\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6150\">\u667a\u6167\u4e4b\u7a97: \u5728\u4e16\u4e0a\u4f60\u5011\u6709\u82e6\u96e3<\/a><\/li>\n<li id=\"menu-item-6158\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6158\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6152\">\u667a\u6167\u4e4b\u7a97: \u611f\u52d5<\/a><\/li>\n<li id=\"menu-item-6167\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6167\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6165\">\u751f\u547d\u7dda: \u7b2c\u5341\u5ea7\u96d5\u50cf<\/a><\/li>\n<li id=\"menu-item-6177\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6177\"><a href=\"http:\/\/eu.cchc-herald.org\/?page_id=6169\">\u751f\u547d\u7dda: 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